To supplement one’s diet with the healthy bacteria bifidobacterium longum and lactobacillus acidophilus, many of us turn to products that are commonly called probiotic acidophilus or acidophilus supplements or even just probiotics . There was a time when acidophilus supplements were typically seen as a stand-alone product, and were usually purchased that way as well. Now, though, the scientific understanding has advanced to make it clear that probiotic acidophilus is most effective when taken with prebiotics. Probiotics and prebiotics work together. To get the most health benefits from your probiotic acidophilus (and there are many!), support it with prebiotics as well.